





Dr Koo Level 3 Retinol | Advanced Renewal Serum
Dr Koo Level 3 Retinol | Advanced Renewal Serum
Dr Koo Private Practice Skincare
10435 Clayton Road
Suite 120
Frontenac MO 63131
United States
Level 3 advances to 5000 IUs of buffered retinol — kind to skin yet powerful enough for visible regeneration. It actively stimulates collagen and elastin to plump and firm, reinforced by essential fatty acids, Vitamin D, and Vitamin E to strengthen the skin barrier against further damage. Hexylresorcinol brightens and evens tone as a gentle surface exfoliation softens lines and restores radiance.
Independent clinical evidence — this formulation
Essex Testing Clinic · 33 women, ages 46–69 · nightly use for 8 weeks · evaluated at baseline, 4 and 8 weeks · each participant compared with her own baseline.
- Fine lines & wrinkles (Visia CR 2.2 imaging): 8.9% improvement at 4 weeks, 13.4% at 8 weeks — 100% of participants improved
- Elasticity (Cutometer): +8.4% at 4 weeks, +16.1% at 8 weeks — 94% improved
- Firmness (Cutometer): 28.6% improvement at 4 weeks — 91% improved
- Radiance (imaging): improved at 4 and 8 weeks — 70% improved at 8 weeks
- Irritation: none observed in any participant at any visit; 97% reported no significant sensitivity compared with other retinols
All improvements above were statistically significant (p<0.001, except radiance at 4 weeks p=0.032). Signed final report on file.
Levels 1, 2 and 4 are the same formulation system at different retinol concentrations, matched to your skin's tolerance and need. The measurements above were taken on Level 3.
